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I’m a pharmacist. So no, I’m not telling you medication is bad. Medication can save lives. It can relieve suffering. And sometimes it’s exactly what someone needs. But it shouldn’t keep us from asking the question. If someone can’t sleep because they’re working 60 hours a week… If they’re anxious because they’re living in a relationship that feels unsafe… If they can’t concentrate because they’re overwhelmed from the moment they wake up… If they’re exhausted because they’ve been carrying everyon
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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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