Hospitalised children predate 19th-century specialist children’s hospitals. Before Lister and anaesthesia, surgery was generally of short duration. In the 18th century, paediatric surgery was ...

Aims Extremely premature infants are at higher risk for intracranial ischaemic and haemorrhagic injuries, which often occur in the first 72 hours after birth. 1 Intraventricular haemorrhages (IVHs) ...

Objectives To determine (1) which maternal and area characteristics are associated with reaching fidelity targets (the expected number of visits mothers should receive at each stage of the programme) ...

Objective To determine whether infants with severe persistent sleep problems are at increased risk of (1) meeting diagnostic criteria for a psychiatric disorder (age 10 years), and (2) having elevated ...

Objective To compare immunological responses of preterm infants to a four-component meningococcal B vaccine (4CMenB; Bexsero) following a 2+1 vs a 3+1 schedule, and to describe reactogenicity of ...

Objective The children's head injury algorithm for the prediction of important clinical events (CHALICE) is one of the strongest clinical prediction rules for the management of children with head ...

Objective To develop an Overall Pediatric Health Standard Set (OPH-SS) of outcome measures that captures what matters to young people and their families and recognising the biopsychosocial aspects of ...

Background The broad-spectrum antiparasitic drug ivermectin is widely used in children, and its use in children weighing < 15 kg is off-label, as little data is available to inform the use of ...

Background The gold standard for diagnosis of meningitis is the isolation of a pathogen from cerebrospinal fluid (CSF) by culture or PCR. However, treatment is routinely commenced based on CSF ...

2 Division of Paediatric Medicine and the Paediatric Outcomes Research Team, The Hospital for Sick Children, University of Toronto, Toronto, Canada 3 Division of General Pediatrics, University ...

Objective To explore the factors contributing to prescribing error in paediatric intensive care units (PICUs) using a human factors approach based on Reason’s ...

Correspondence to Prof Dominic Wilkinson, Oxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, Oxfordshire, UK; dominic.wilkinson{at}philosophy.ox.ac.uk The prospect of vaccinating ...