Differential expression can be used to identify genes that are likely to be involved in the development and progression of cancer. To detect genes whose expression is decreased in prostate cancer, we ...

Clozapine is an atypical antipsychotic drug with unique pharmacological and therapeutic properties. Unlike the typical antipsychotic drug, haloperidol, clozapine does not cause extrapyramidal side ...

Advances in high-throughput genome sequencing demand the development of more efficient ways of examining gene expression at a cellular level. During recent years, polymerase chain reaction (PCR)-based ...

The increased use of genomics in medical and pharmaceutical research has created unprecedented opportunities for scientists, physicians and patients. Recent technological advances that allow ...

This is a preview. Log in through your library . Abstract We have systematically characterized gene expression patterns in 49 adult and embryonic mouse tissues by using cDNA microarrays with 18,816 ...

The following filter criteria for genes differentially expressed were used: PDAC versus normal pancreas (bulk tissue), PDAC versus normal pancreas (microdissected normal ductal cells), and PDAC versus ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

Individual Patient Data Meta-Analysis of Docetaxel Administered Once Every 3 Weeks Compared With Once Every Week Second-Line Treatment of Advanced Non–Small-Cell Lung Cancer Tumor tissue was collected ...

Clinical Role of Multidrug Resistance Protein 1 Expression in Chemotherapy Resistance in Early-Stage Breast Cancer: The Austrian Breast and Colorectal Cancer Study Group Core biopsies from 24 patients ...