Two-component regulatory systems constitute a widespread mechanism by which bacteria detect and adapt to antimicrobial threats. Each system comprises a membrane-associated sensor histidine kinase that ...
A team has uncovered how a common bacterial pathogen uses a single protein to quietly undermine the human immune system, by both shutting down key warning signals and blocking the cell’s ability to ...
Discoveries may help to explain why some bacteria are hard to eliminate, and also point to potential future approaches to improving antibiotic effectiveness.