This protocol describes a primary neuronal model of formation of α-synuclein (α-syn) aggregates that recapitulate features of the Lewy bodies and Lewy neurites found in Parkinson's disease brains and ...

The enantioselective addition of water to olefins in an aqueous environment is a common transformation in biological systems, but was beyond the ability of synthetic chemists. Here, we present the ...

Osaka, Japan - Synthesizing pharmaceuticals for cancer, viral diseases, and other medical conditions is slow work. A particularly challenging chemical transformation is to start with what's known as ...

Synosia Therapeutics has announced the first clinical study results showing that SYN-118 provides clinically meaningful benefits to Parkinson’s patients, has a good safety profile and is well ...

As Part of an Exploratory Outcome, ABLi Therapeutics Used CND's Syn-One Biomarker Services to Quantify and Visualize a ...

Synthesizing pharmaceuticals for cancer, viral diseases, and other medical conditions is slow work. A particularly challenging chemical transformation is to start with what's known as an unactivated ...

In a development that could revise organic chemistry textbooks, a new catalytic version of alkene dichlorination makes the reaction more versatile. Now, researchers have devised the first catalytic ...