Original story from Mayo Clinic (MN, USA). A new technique for tagging senescent cells – which are associated with numerous diseases – has been developed. When it comes to treating disease, one ...
Hosted on MSN
Sneaky senescent cells that resist cancer treatment can provide druggable lung cancer target
Senescent fibroblasts are aging cells that no longer divide and protect against tumor development. Yet two decades have gone by since cell biologist Judith Campisi, Ph.D., paradoxically demonstrated ...
Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant ...
T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...
“[...] cancer immunotherapy based on tumor-associated senescent cells and other types of senescent cells may achieve exciting outcomes beyond cancer therapy ...
In a recent study published in Nature Aging, researchers investigated whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis. Senescent cells, responsible for aging, amass in ...
A research team led by Professor Takuya Yamamoto (Department of Life Science Frontiers) and Professor Yasuhiro Yamada at the University of Tokyo has developed a novel in vivo system that reveals how ...
A new, label-free method for identifying aged human cells has been developed. Researchers from Tokyo Metropolitan University (Japan) have created a new way of telling ‘aged’ human cells apart from ...
T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results