Sample sizes for single-stage phase II clinical trials in the literature are often based on exact (binomial) tests with levels of significance (alpha (α) <5% and power >80%). This is because there is ...

Mainland and Sutcliffe [1953] and Bennett and Hsu [1960] have calculated the power of the exact conditional (Fisher-Irwin) test for differences between proportions. We have performed similar ...

What is Fisher's exact test? Fisher’s exact test is a statistical hypothesis test used to assess the association between two binary variables in a contingency table and is particularly useful when ...

Exact statistics can be useful in situations where the asymptotic assumptions are not met, and so the asymptotic p-values are not close approximations for the true p-values. Standard asymptotic ...

Testing genetic markers for Hardy–Weinberg equilibrium (HWE) is an important tool for detecting genotyping errors in large-scale genotyping studies. For markers at the X chromosome, typically the χ 2 ...