Measuring the levels of vitronectin in urine could improve the detection of kidney fibrosis, according to scientists from the Germans Trias i Pujol Research Institute (IGTP) and University Hospital ...

Although antifibrotic agents can contribute to suppressing renal function decline when administered in combination with existing treatments for chronic kidney disease, drugs targeting kidney fibrosis ...

CHAMPAIGN, Ill. — A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis — a serious complication of diabetes ...

Renal fibrosis represents a key driver of the pathology of chronic kidney disease (CKD), marked by fibroblast activation, tubular damage and inflammation. Previous work found that cyclic guanosine ...

Using human-induced pluripotent stem cell-derived kidney organoids, researchers from Science Tokyo uncovered how abnormal Hippo signaling drives fibrosis in nephronophthisis, a genetic kidney disorder ...

Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, ...

ATYR0101 interacts with LTBP-1 to induce myofibroblast apoptosis through a novel anti-fibrotic mechanism to reduce fibrosis and fibrotic markers in models of lung and kidney fibrosis. SAN DIEGO, Dec.

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis - a serious complication of diabetes and a leading ...

An easy-to-use nomogram accurately predicts which patients with lupus nephritis have IFTA. Investigators have created a nomogram that predicts the probability of interstitial fibrosis/tubular atrophy ...

Vertex on track for “five launches in five disease areas over a five-year period” through emerging pain and renal franchises.