Protein hydrophobicity is a fundamental driver of protein folding dynamics, underpinning the formation of a central hydrophobic core that stabilises the three-dimensional structure amid an aqueous ...

The cells in living organisms are constantly making proteins. Ribosomes, the RNA-protein complexes that make other proteins, ...

Scientists discovered a role played by ribosomes during the folding of new proteins in cells. Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular machines ...

For those outside the chemistry cognoscenti, the announcement might have seemed little more than researchers patting each other on the back. But the question of protein folding had plagued scientists ...

"Because of the nature of this type of misfolding, the protein gets stuck," Jiang said. "The protein must backtrack in the folding process to correct the mistake, which takes time and is energetically ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.

Google DeepMind’s work with AlphaFold has been nothing short of a miracle, but it is computationally expensive. With that in mind, Apple researchers set off to develop an alternative method to use AI ...