A review delves into the significance of biomolecular condensation in cellular processes, the impact of aberrant phase separation on diseases such as neurodegenerative diseases, cancers, and ...

You essentially have multiple ways to tune condensate formation with just adding this one polyubiquitin molecule," notes Castañeda. While their research merely scratches the surface of how ...

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing cellular life, yet why some RNAs cluster more readily than ...

Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion ...

Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...

A new study published in Cell Reports titled, “Kinase condensates enrich ATP and trigger autophosphorylation,” suggests that cellular phase separation, a mechanism that organizes biomolecules into ...

Researchers at Baylor College of Medicine have identified a cellular protein, tubulin, that can redirect two of the most ...

From plants to animals, all living things depend on proteins to help their cells function properly. In certain cases, like when under stress in response to heat or toxins, some proteins within the ...

Researchers are working to understand how protein quality control works in cells. From plants to animals, all living things depend on proteins to help their cells function properly. In certain cases, ...