In a new discovery, chronic pain has been shown to be physiologically different from acute pain and now scientists have the roadmap for how to target it. Researchers from the University of Aberdeen, ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

For millions of older adults worldwide, life is often tarnished by the persistent, gnawing presence of chronic pain ...

Rheumatoid arthritis is a chronic autoimmune disease that affects millions of people worldwide. This disease prompts the immune system to mistakenly attack body tissues, particularly joints, leading ...

The spino-ponto-amygdaloid pathway is a major ascending circuit relaying nociceptive information from the spinal cord to the brain. Potentiation of excitatory synaptic transmission in the parabrachial ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

In a study published in Nature Human Behaviour on Oct. 9, researchers led by Profs. TU Yiheng and HU Li from the Institute of Psychology of the Chinese Academy of Sciences have uncovered a neural ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Subscribe to our newsletter for the ...