Targeting senescent cells with dasatinib-quercetin preserves disc structure and modulates degeneration-associated pathways in a mouse model.

Targeting senescent cells with dasatinib–quercetin preserves disc structure and modulates degeneration-associated ...

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration." In this study, led by ...

Intervertebral disk tissue was obtained from 35 patients undergoing surgery for chronic degenerative disease (n = 25) or an acutely herniated disk (n = 12). Of note, 48% of patients with degenerative ...

Karin Wuertz-Kozak described her lab test equipment as a gym for cells. Stretching and compressions tests using bioreactors—her lab equipment—can make a difference in understanding how cells respond ...

Background Lower back pain occurs more frequently among volleyball than other players and one of the main course affecting their performance on the court. Objective To identify the reason of the lower ...

Therapies that target aging cells early pave the way to easing back pain. "Once intervertebral discs start to degenerate, there is very little regeneration that happens," says Dr. Risbud. "But our ...

Did you know that chronic lower back pain is the single greatest cause of years lived with disability worldwide? One of the main causes of lower back pain is lumbar degenerative disc disease. This is ...

Did you know that chronic lower back pain is the single greatest cause of years lived with disability worldwide? One of the main causes of lower back pain is lumbar degenerative disc disease. This is ...