More people in the United States are on antidepressants, as a percentage of the population, than any other country in the world. And yet the drugs’ efficacy has been hotly debated. Some believe that ...

Key points SSRIs work for many people with depression. Yet, we still don't entirely understand how they work. Some with depression will do better receiving psychotherapy over medication; some a ...

A patient asked me recently how many times have I been told that antidepressants are not any better than placebos in the treatment of depression? I responded: “I don’t know because I can’t count that ...

When they work, antidepressant medications may take weeks or months to alleviate symptoms of depression. Progress in developing new and more effective antidepressant treatments has been limited, ...

Questions about how effective antidepressants are have swirled for years, but some new research suggests people who take the drugs are actually more likely to experience relapses of depression. Casey ...

Three medical experts review the evidence around how antidepressants may affect the gut microbiome, and what this could mean ...

Taking medication for depression can feel like a huge step, and it’s normal to worry about what it means for both your current and long-term health. But, if you’ve been diagnosed with depression and ...

Imagine your brain is Instagram. Then serotonin—a neurotransmitter that governs your mood—is the tech that allows one brain nerve cell to slip into another’s DMs. These messages tell your body what to ...

Scientists have been debating the efficacy of antidepressants for decades. The latest paper to throw its hat into the ring concludes that there is little evidence to show that they perform better than ...