An international task force of medical experts recently proposed major revisions to the way doctors measure treatment success for a common–and often severe–skin complication of stem cell ...

1 Rash < 25% Bilirubin 2-2.9 mg/dl Diarrhea 500-1000cc/d or biopsy-proven upper GI involvement 2 Rash 25-50% Bilirubin 3-6 mg/dl Diarrhea 1000-1500cc/d 3 Rash > 50% Bilirubin 6.1-15 mg/dl Diarrhea ...

Consensus Project Task Force recently published a report of their refined approach in the journal, Transplantation and ...

Q: My son received a bone marrow transplant after the chemotherapy wiped out his acute lymphocytic leukemia, and now the doctors say the transplanted cells are attacking his body. Please explain more ...

For patients with haploidentical hematopoietic cell transplantation (haplo-HCT), the addition of itacitinib to standard graft versus host disease (GvHD) prophylaxis is well tolerated and results in ...

Acute graft-versus-host disease (aGVHD) is a life-threatening complication after allogeneic hematopoietic stem cell ...

Transitioning to a 0.6 mg/kg monthly dose of Niktimvo showed a 94.7% overall response rate in cGVHD patients. Increased severe side effects were observed with the monthly dose, likely due to longer ...

Graft-versus-host disease (GVHD) following liver transplantation remains a rare but devastating complication, characterised by donor immunocompetent cells initiating an immune attack against host ...

Xervyteg demonstrated a 62% GI overall response rate at day 28, significantly exceeding historical controls, with durable responses and survival benefits over one year. The safety profile was ...