A recent study provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains ...

Factor VII deficiency is a rare, autosomal recessive bleeding disorder marked by reduced levels or dysfunction of coagulation factor VII, a crucial initiator of the extrinsic coagulation cascade.

The expression of tissue factor (TF) is limited in normal tissues to the perivascular compartment where it acts as the receptor for the serin protease factor VIIa. This signaling axis triggers the ...

A recent study led by MedUni Vienna provides new insights into the mechanisms of coagulation in persons with hemophilia A, the most common form of hemophilia. The research team was able to show that ...

To understand the pharmacology and mechanism of action of ximelagatran, a review of the formation and function of thrombin is warranted. [10] The generation of thrombin is limited under normal ...