Technological and conceptual advancements in recent years have created the opportunity to revisit the transcription factory model with newer insights into the mechanisms underlying the formation and ...
Gene expression is regulated by a complex interplay between DNA sequence, chromatin structure and transcription factor binding 1,2,3. Numerous methods to characterize cellular epigenomes have been ...
Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...