Scientists share detailed, complete images of a viral structure called the Ebola virus nucleocapsid. This breakthrough may accelerate the development of antivirals that target this viral structure to ...

Filoviruses—such as Ebola and Marburg viruses—can cause hemorrhagic fevers with up to 90% lethality. Not only that, but there are very few tools (vaccines or drugs) to combat them. Now, scientists at ...

Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus). Inmazeb (REGN-EB3), developed by ...

Ebola virus, one of the deadliest pathogens, has a fatality rate of about 50%, posing a serious threat to global health and safety. To address this challenge, researchers at the University of ...

The model on the left shows how the Ebola virus stalk has a compact conformation, which blocks the site where mAb 3A6 would bind. The model on the right shows how this portion of the stalk can adopt ...

LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus). Inmazeb (REGN-EB3), ...

One day after the first Ebola death in the United States, researchers at UVa announced they had determined the structure of a part of the virus they believe plays an important role in replication — ...

Researchers have identified a cellular pathway that keeps Ebola virus from exiting human cells, with implications for developing new antivirals. In their evolutionary battle for survival, viruses have ...

New research led by scientists at La Jolla Institute for Immunology (LJI) reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus ...

Ebola virus and Marburg virus are both highly contagious filoviruses and are among the most lethal viruses known. Patient deaths are often a consequence of gastrointestinal damage leading to diarrhea ...