In both traditional acupuncture theory and modern medical experience, acupoints are central to therapeutic outcomes, yet their biological nature has remained controversial. Conventional models assume ...

The burden of chronic pain. Source: GoodIdeas / Shutterstock Nerve sensitization often contributes to chronic pain states, such as back pain, migraines, and irritable bowel. Sensitization is an ...

Findings suggest that including slowly repeated evoked pain (SREP) in quantitative sensory testing protocols may enhance assessments of altered pain modulation in different pain conditions. Study ...

This first-of-its-kind study by researchers at The Ohio State University Wexner Medical Center and College of Medicine and University of Michigan Medical School explored one potential mechanism – ...

Please provide your email address to receive an email when new articles are posted on . Central sensitization may be an important underlying factor that complicates the treatment of chronic pain and ...

Please provide your email address to receive an email when new articles are posted on . Patients undergoing total knee arthroplasty with preoperatively identified central sensitization may experience ...

Central sensitization in chronic back pain manifested as greater unpleasantness to both pressure and sound, with stronger and more specific amplification for auditory stimuli than mechanical ...

Gabapentin is a gamma-aminobutyric acid derivative, and was approved for the treatment of neuropathic pain by the U.S. Food and Drug Administration in 2002. However, little evidence is available on ...

Scientists have long noted a connection between opioid use disorder (OUD) and chronic pain, however brain mechanisms linking OUD and chronic pain are poorly understood. A new study has explored one ...