Persistent viral infections pose a unique challenge to the immune system. Prolonged antigen exposure drives T cells into a state of exhaustion — a ...

Cancer arises when the normal controls on cell growth, differentiation and death are subverted. Under physiological conditions, cells proliferate only in response to external stimuli, replicate their ...

Neural stem cells (NSCs) sit at the heart of brain development, lifelong neurogenesis, and the brain’s capacity to respond to injury and disease. Their fate ...

Researchers led by Didier Trono’s group at EPFL have uncovered a crucial survival tactic employed by cancer cells. The scientists identified a group of proteins, known as KRAB zinc finger proteins ...