Ataxia telangiectasia (AT) is a recessive childhood disease caused by mutations in the ATM (AT-mutated) gene. The hallmark of the disease is progressive neurodegeneration that eventually affects all ...
Gastric cancer cell lines, particularly those with low levels of ataxia telangiectasia mutated (ATM), a key activator of DNA damage response, are sensitive to the poly (ADP-ribose) polymerase ...
The ATM protein is a key signaling kinase that is activated by DNA damage and ionizing radiation. In the January 30 Nature, Christopher Bakkenist and Michael Kastan at St Jude Children's Research ...
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