The New England Journal of Medicine

Evaluation of Adrenocortical Function with Intramuscular Injection of ACTH Gel

THE response of the adrenal cortex to intensive stimulation with exogenous ACTH provides an excellent guide to the functional status of the adrenal cortex under most circumstances. Tests based on this ...
Nature

Long-term pituitary function following transsphenoidal surgery for non-functional pituitary neuroendocrine tumor with apoplexy: a single-center retrospective analysis

Pituitary apoplexy is an acute and potentially life-threatening clinical syndrome caused by hemorrhage and/or infarction of a pituitary adenoma. Headache of sudden and severe onset is the main symptom ...
The New England Journal of Medicine

ACTH-Producing Tumor of the Pituitary Gland

THE association of adrenal hyperplasia with basophil tumors of the pituitary gland was first suggested by Cushing. 1 This type of tumor has since been thought to be at least one cause of Cushing's ...
Nature

Nucleus accumbens deep-brain stimulation efficacy in ACTH-pretreated rats: alterations in mitochondrial function relate to antidepressant-like effects

Symptomatically, depressive periods are characterized by decreased energy, paralleled by reduced brain energy generation. 1, 2 This is highlighted by clinical studies examining glucose utilization, ...
CMAJ

Short ACTH stimulation test for adrenal reserves of cortisol, not adrenal function

We agree with the interpretation of the short ACTH stimulation test described by Deeba Syeda and associates. In the case that we described,1 a long ACTH stimulation test was unnecessary because of the ...
Medical Xpress

Study summarizes physiological functions of pituitary hormones in non-classical organs

The hypothalamus–pituitary–target gland axis has been recognized as a fundamental functional framework of the mammalian endocrine system. The anterior pituitary gland synthesizes and secretes multiple ...