Shapiro served as Deputy Assistant Secretary of Defense for the Middle East until January—charged with, among other things, considering scenarios in which tensions between Israel and Iran escalated into all-out war and preparing U.

Experts suggest the U.S. has a strategic opportunity to leverage Iran's weakened position for a nuclear deal after Israel's targeted strikes on Iranian nuclear and military sites.

Iran launched multiple deadly waves of missiles and drones toward Israel into Saturday morning following Israel’s unprecedented strikes aimed at destroying Iran’s nuclear program and decapitating its military leadership.

Trump told the Wall Street Journal that he knew all about Israel’s plan ahead of time, that he wasn’t given a mere “heads-up.”

Fox News’ Alex Hogan and Mark Meredith report on the strikes between Israel and Iran, and reaction from the United States. Heritage Foundation senior fellow Brent Sadler joins ‘Fox News Live’ to analyze the future of Iran’s nuclear program.

Iranian officials have repeatedly denied seeking a nuclear weapon. The United States and Iran have held five rounds of negotiations toward achieving an agreement that would limit Iran's nuclear activities in exchange for sanctions relief, with a sixth round of talks scheduled for Sunday.

Israel's Prime Minister Benjamin Netanyahu says his country will strike "every site and every target of the ayatollah regime" in Iran.

The Israeli military operation against Iran’s nuclear enrichment facilities and ballistic missile program and the US reaction has set up a test for US President Donald Trump and his campaign promise to keep the United States out of foreign conflicts.

Israel and Iran opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday that set off explosions in the Iranian capital of Tehran. Israel said it targeted nuclear and military facilities,